| Echocardiographic predictors of symptomatic patent ductus arteriosus in extremely-low-birth-weight preterm neonates. | |
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MedLine Citation:
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PMID: 20182434 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Identify echocardiographic parameters at <or=4 day postnatal that predict the subsequent need for closure of a clinically significant patent ductus arteriosus (sPDA) in extremely-low-birth-weight neonates (ELBW). STUDY DESIGN: Serial echocardiograms obtained in 115 ELBW at <or=10 day postnatal were examined to estimate PDA size using the PDA:left pulmonary artery (LPA) diameter ratio: >or=1 indicated a large PDA, <1 but >or=0.5 moderate, and <0.5 small. Sensitivity, specificity, and positive predictive values (PPV) were determined for ELBW <27 weeks and >or=27 weeks gestational age. RESULT: Neonates with moderate to large PDA at <or=4 day had 15-times greater likelihood of requiring treatment for sPDA than those with a small PDA (95% confidence interval (CI): 5.6-41). Sensitivity, specificity and PPV of the PDA:LPA at <27 weeks was 80, 86 and 92%, respectively. CONCLUSION: A moderate to large PDA determined from the PDA:LPA ratio at <or=4 day postnatal identifies neonates <27 week gestation who subsequently require closure of a PDA. |
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Authors:
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F G Ramos; C R Rosenfeld; L Roy; J Koch; C Ramaciotti |
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Publication Detail:
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Type: Journal Article Date: 2010-02-25 |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 30 ISSN: 1476-5543 ISO Abbreviation: J Perinatol Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-29 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 535-9 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ductus Arteriosus, Patent
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classification,
ultrasonography* Gestational Age Humans Infant, Extremely Low Birth Weight* Infant, Newborn Male Predictive Value of Tests Regional Blood Flow Retrospective Studies Severity of Illness Index* |
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