Document Detail


Echocardiographic prediction of patent ductus arteriosus in need of therapeutic intervention.
MedLine Citation:
PMID:  20874741     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aim:  To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment. Methods:  Forty-five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24 ± 6 and 72 ± 6 h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA/Ao) ratio and Doppler pixels representing ductal shunting. Results:  Twenty-eight infants had a PDA with a detectable left-to-right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a sensitivity of 89%, a specificity of 70%, a positive likelihood ratio of 2.97 and a negative likelihood ratio of 0.16 at the age of 72 h. The efficacy of the method at 72 h of age was 84%. The corresponding efficacy of the pulsatile Doppler curve was 72%, percentage of green colour pixels 63% and the LA/Ao ratio 53%. Conclusion:  Ductus diameter appears to be the most important variable in determining the need for therapeutic intervention for PDA in preterm infants.
Authors:
S Harling; I Hansen-Pupp; A Baigi; E Pesonen
Publication Detail:
Type:  Journal Article     Date:  2010-10-13
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  100     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  231-5     Citation Subset:  IM    
Copyright Information:
© 2010 The Author(s)/Acta Paediatrica © 2010 Foundation Acta Paediatrica.
Affiliation:
Department of Paediatrics, Halmstad Hospital, Halmstad, Sweden Department of Paediatrics, Skåne University Hospital and Skåne University, Skåne, Sweden General Practice and Public Health, Halland County Council, Falkenberg, Sweden.
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