Document Detail


Echocardiographic findings in patients with Behçet's disease.
MedLine Citation:
PMID:  16490443     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Case-controlled studies have shown that the prevalence of left ventricular (LV) diastolic dysfunction is higher in patients with Behçet's disease. However, there are no data evaluating the value of Doppler tissue imaging (DTI) in Behçet's disease. The aim of this study was to evaluate the cardiac involvement and the LV function at rest and at the end of isometric exercise by pulse-wave Doppler and DTI methods in patients with Behçet's disease. Fifty-four patients with Behcet's disease and 50 control subjects were studied. Dimensions of cardiac chambers, aortic root dimension, valvular abnormalities, and systolic function were similar in both groups. The mean E/A ratio was significantly lower in patients than controls (1.22 +/- .09 vs 1.36 +/- 0.30, p = 0.01). The E/A ratio was <1 in 12 patients (22%) and in 3 controls (6%) (p = 0.02). By DTI, no difference was found in the mean S-, e-, and a-wave velocities, and e/a ratio between the 2 groups. The e/a ratio was <1 in 13 patients (24.1%) and in 7 controls (14%) (p = 0.2) by DTI. There were no differences in the mitral pulse-wave Doppler and DTI parameters in patient and control groups at the end of exercise. The prevalence of cardiac pathology in Behçet's disease did not differ appreciably from the controls. In conclusion, the LV systolic and diastolic functions in the patients with Behçet's disease and controls were similar not only at rest but also at the end of exercise.
Authors:
Abdi Bozkurt; Onur Akpinar; Soner Uzun; Ayşe Akman; Didem Arslan; Ahmet Birand
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Publication Detail:
Type:  Journal Article     Date:  2006-01-11
Journal Detail:
Title:  The American journal of cardiology     Volume:  97     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-21     Completed Date:  2006-04-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  710-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, Cukurova University, School of Medicine, Adana, Turkey. abozkurt@cu.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Adult
Behcet Syndrome / epidemiology,  physiopathology,  ultrasonography*
Blood Flow Velocity
Blood Pressure
Case-Control Studies
Echocardiography*
Echocardiography, Doppler, Pulsed
Electrocardiography
Exercise
Exercise Test
Female
Heart Rate
Humans
Male
Myocardial Contraction
Prevalence
Turkey / epidemiology
Ventricular Dysfunction, Left / epidemiology,  physiopathology,  ultrasonography
Ventricular Function, Left

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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