| Echocardiographic evaluation in type 1 diabetic patients on waiting list for isolated pancreas or kidney-pancreas transplantation. | |
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MedLine Citation:
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PMID: 15110556 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Type 1 diabetic patients may display abnormalities of left ventricular geometry and systolic and diastolic function. Patients on the waiting list for solitary pancreas or kidney-pancreas transplantation were evaluated by Doppler echocardiography to assess left ventricular geometry and systolic and diastolic function, and correlate these parameters with clinical characteristics. We evaluated 78 patients including 45 men with an overall mean age of 39.5 +/- 7.2 years and a disease duration of 24 +/- 9.8 years. Among these 78 patients, 13 showed isolated retinopathy, 9 isolated arterial hypertension, 45 concomitant retinopathy and hypertension and overt nephropathy, while 11 were free of complications. The results of our study showed an increased left ventricular mass and abnormal diastolic function among patients with simultaneous target organ complications and with hypertension, as has been reported in many previous studies. In contrast study patients with no complications showed normal left ventricular structure and function. This finding conflicts with data from several reports in the medical literature in which diastolic impairment was present in type 1 diabetic patients at an early stage of disease and with no evident microvascular and macrovascular complications. |
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Authors:
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L Rondinini; R Mariotti; B Cortese; G Rizzo; P Marchetti; R Giannarelli; A Coppelli; N Fossati; U Boggi; M Mariani |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Transplantation proceedings Volume: 36 ISSN: 0041-1345 ISO Abbreviation: Transplant. Proc. Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-04-27 Completed Date: 2004-11-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0243532 Medline TA: Transplant Proc Country: United States |
Other Details:
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Languages: eng Pagination: 457-9 Citation Subset: IM |
Affiliation:
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Cardiac and Thoracic Department, Pisa, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Diabetes Mellitus, Type 1 / surgery, ultrasonography* Diabetic Angiopathies / ultrasonography Diabetic Nephropathies / surgery Diastole Echocardiography* Female Humans Kidney Transplantation* Male Pancreas Transplantation* Renal Dialysis Waiting Lists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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