Document Detail

Echocardiographic dimensions in borderline and sustained hypertension.
MedLine Citation:
PMID:  158966     Owner:  NLM     Status:  MEDLINE    
Echocardiographic dimensions and hemodynamic indexes were determined in 42 patients with borderline hypertension and in 22 with sustained hypertension and the results were compared with findings in 33 normal subjects. In patients with borderline hypertension the thickness of the interventricular septum (IVS) was significantly increased (P less than 0.001), whereas the posterior wall PW) thickness remained within normal range. The IVS/PW ratio was significantly elevated (P less than 0.001) and was correlated negatively with the cardiac index (P less than 0.01) and positively with the preejection period (P less than 0.01). In patients with sustained hypertension a symmetric cardiac hypertrophy was observed, and there was a significant positive correlation between the IVS/PW ratio and diastolic pressure (P less than 0.05). The study suggested that (1) in sustained hypertension the symmetric cardiac hypertrophy was secondary to a progressive increase in pressure load, whereas (2) in borderline hypertension the asymmetric cardiac hypertrophy could not be directly related to the level of blood pressure and was probably associated with abnormalities of the sympathetic nervous system.
M E Safar; J P Lehner; M I Vincent; M T Plainfosse; A C Simon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  44     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1979-12-29     Completed Date:  1979-12-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  930-5     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure
Cardiac Output
Cardiomegaly / complications
Heart Rate
Hypertension / complications,  physiopathology*
Renin / blood
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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