Document Detail


Echocardiographic classification of chronic ischemic mitral regurgitation caused by restricted motion according to tethering pattern.
MedLine Citation:
PMID:  15341868     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although the mechanism of ischemic mitral regurgitation (MR) is understood, the echocardiographic picture of ischemic MR is not homogeneous. Ninety-two consecutive patients with chronic ischemic MR due to restricted motion were divided into two groups according to tethering pattern: the asymmetric group with predominant posterior tethering of both leaflets (54 patients) and the symmetric one with predominant apical tethering of both leaflets (38 patients). The mitral deformation indexes, LV global (volume, function and sphericity) and local (papillary muscle displacements and regional wall motion score index) remodeling were evaluated. All indexes of global LV remodeling were significantly higher in the symmetric than asymmetric group (all p < 0.0001), such as the posterior and lateral displacement of the anterior papillary muscle (both p < 0.04), the papillary muscle separation and the anterior papillary muscle wall motion index (both p < 0.0001). The origin as well as the direction of the jet was central in all patients of the symmetric group. In the asymmetric one the origin was central in 78% of the cases and arising from the medial commissure in 22% whereas the jet direction was posterior and central in 83% and 17% of patients, respectively. Therefore, it is possible to distinguish at least two subgroups of patients with ischemic MR due to restricted motion on the basis of tethering pattern, different degree of local and global LV remodeling and characteristics of the regurgitant jet.
Authors:
Eustachio Agricola; Michele Oppizzi; Francesco Maisano; Michele De Bonis; Arend F L Schinkel; Lucia Torracca; Alberto Margonato; Giulio Melisurgo; Ottavio Alfieri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  5     ISSN:  1525-2167     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-02     Completed Date:  2004-12-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  326-34     Citation Subset:  IM    
Affiliation:
Division of Non-Invasive Cardiology, Department of Cardiology, San Raffaele Hospital, Via Olgettina 60, 20132 Milano, Italy. agricola.eustachio@hsr.it
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MeSH Terms
Descriptor/Qualifier:
Aged
Chi-Square Distribution
Echocardiography*
Female
Humans
Male
Middle Aged
Mitral Valve / ultrasonography
Mitral Valve Insufficiency / physiopathology,  ultrasonography*
Myocardial Ischemia / physiopathology,  ultrasonography*
Reproducibility of Results
Ventricular Remodeling
Comments/Corrections
Comment In:
Eur J Echocardiogr. 2004 Oct;5(5):313-7   [PMID:  15341864 ]

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