Document Detail

Echocardiographic characteristics in patients > or =100 years of age.
MedLine Citation:
PMID:  18082529     Owner:  NLM     Status:  MEDLINE    
The centenarian population is increasing, and patients > or =100 years old are encountered more frequently in clinical practice. Cardiovascular disease is the most common cause of death in this subset of patients. We report the echocardiographic characteristics of 63 hospitalized centenarians. Patients ranged in age from 100 to 112 years and were admitted to the hospital for a variety of diagnoses. The mean left ventricular end-diastolic dimension was 3.9 +/- 0.7 cm (2.8 to 5.8), the mean left ventricular end-systolic dimension was 1.8 +/- 0.7 cm (0.8 to 3.5), the mean ventricular septal thickness was 1.2 +/- 0.25 cm (0.8 to 1.9), the mean left ventricular posterior wall thickness was 1.1 +/- 0.14 cm (0.8 to 1.6), the mean left ventricular ejection fraction was 84% +/- 11% (49% to 97%), the mean aortic root diameter at the level of the sinuses was 3.3 +/- 0.4 cm (2.1 to 4.1), the mean left atrial dimension was 4.5 +/- 0.7 cm (3.1 to 7), the mean right ventricular end-diastolic dimension was 3.4 +/- 0.6 cm (2.0 to 4.8), and the mean pulmonary artery systolic pressure was 37 +/- 14 mm Hg. Moderate or severe valvular lesions were common, including aortic stenosis (27%), aortic regurgitation (17%), mitral regurgitation (22%), and tricuspid regurgitation (28%). In conclusion, centenarian hearts have important differences from younger hearts, including more hypertrophied left ventricle, higher ejection fraction, higher pulmonary artery systolic pressure, and more prevalent significant valvular heart disease.
Adnan Sadiq; Muhaddis Choudhury; Kamran Ali; Elsayed Mohamed; Vijay Shetty; Chaim Kabalkin; Alvin Greengart
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Publication Detail:
Type:  Journal Article     Date:  2007-10-29
Journal Detail:
Title:  The American journal of cardiology     Volume:  100     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-17     Completed Date:  2008-02-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1792-4     Citation Subset:  AIM; IM    
Department of Cardiology, Maimonides Medical Center, Brooklyn, New York, USA.
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MeSH Terms
Aged, 80 and over
Coronary Artery Disease / pathology
Heart / anatomy & histology*
Heart Diseases / epidemiology,  ultrasonography
Heart Septum / anatomy & histology,  ultrasonography
Heart Valve Diseases / epidemiology
Heart Ventricles / anatomy & histology,  ultrasonography
Hypertension / pathology
Retrospective Studies

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