Document Detail

Echocardiographic assessment of conjoined twins with congenital heart disease in Shanghai.
MedLine Citation:
PMID:  19392843     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of this study is to improve the diagnosis of congenital heart disease in conjoined twins using echocardiography. METHODS: Six sets of conjoined twins at Shanghai Children's Medical Center and Xin-Hua Hospital from 1980 to 2006 were assessed retrospectively. Cardiac anomalies of varying degrees of severity were first evaluated using 2D echocardiography. Tissue Doppler imaging (TDI) was then performed if fused ventricles were suspected. Peak systolic velocities, peak systolic strain rates, and peak systolic strains at the fused myocardium were quantitatively measured using strain rate imaging (SRI). If the M-mode echocardiographic image was poor or difficult to measure, the myocardial performance index (MPI) of the left ventricle was calculated. RESULTS: Intracardiac anomalies were diagnosed correctly using echocardiography and confirmed by surgical findings. Cardiac functional assessment using MPI demonstrated heart failure in three out of the eight individuals. Subtle conjunction of the ventricles, however, were more difficult to visualize and two sets of conjoined twins with fused hearts could not be clearly demonstrated by echocardiography. In one case of suspected ventricular wall conjunction, TDI showed separate ventricular myocardia which was confirmed at surgery. CONCLUSIONS: Intracardiac anomalies and ventricular function can be readily demonstrated by echocardiography, but subtle conjunction of the ventricles may be more difficult to visualize. TDI may be required if there is uncertainty about the degree of cardiac fusion.
Yu-Qi Zhang; Lan-Ping Wu; Li-Jun Wu; Guo-Zhen Chen; Kun Sun; Zhi-Fang Zhang; Rong Shen
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Publication Detail:
Type:  Journal Article; Twin Study     Date:  2009-04-08
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  26     ISSN:  1540-8175     ISO Abbreviation:  Echocardiography     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-14     Completed Date:  2009-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  691-8     Citation Subset:  IM    
Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University, Shanghai, China.
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MeSH Terms
Heart Defects, Congenital / ultrasonography*
Infant, Newborn
Twins, Conjoined*
Ultrasonography / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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