| Echocardiographic Epicardial Fat Thickness Is Associated with Carotid Intima-Media Thickness in Patients with Metabolic Syndrome. | |
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MedLine Citation:
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PMID: 21827549 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Carotid intima-media thickness (CIMT) is a potential indicator of subclinical atherosclerosis in patients with metabolic syndrome (MetS). Epicardial fat thickness (EFT) is suggested as a new cardiometabolic risk factor. We investigated the association between EFT and CIMT in patients with MetS. Methods: Forty patients with MetS were compared with 40 age- and sex-matched subjects without MetS in terms of echocardiographic EFT, CIMT, anthropometric measurements, and metabolic profile in this cross-sectional study. Results: The waist circumference, total and LDL-cholesterol, fasting glucose, triglycerides, systolics and diastolic blood pressure levels, hs-CRP, and homeostasis model assessment index for insulin resistance (HOMA-IR) were significantly increased in patients with MetS. The EFT and CIMT were also increased significantly in patients with MetS compared to controls (7.2 ± 2 mm vs. 5.7 ± 1.9 mm; P = 0.001, 0.74 ± 0.1 mm vs. 0.59 ± 0.1 mm; P < 0.01, respectively). Echocardiographic EFT was the only independent predictor of CIMT in the multivariate analysis (standardized β coefficient = 0.74, P < 0.001). Conclusion: EFT is associated with increased CIMT in patients with MetS. (Echocardiography ****;**:1-6). |
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Authors:
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Cihan Sengul; Cihan Cevik; Olcay Ozveren; Vecih Oduncu; Aysegul Sunbul; Taylan Akgun; Mehmet Mustafa Can; Ender Semiz; Ismet Dindar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-9 |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: - ISSN: 1540-8175 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-8-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011, Wiley Periodicals, Inc. |
Affiliation:
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Division of Cardiology, Goztepe Medical Park Hospital, Istanbul, Turkey Division of Adult Cardiology, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas Division of Cardiology, Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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