Document Detail

Echinocytosis in horses: 54 cases (1990).
MedLine Citation:
PMID:  8468229     Owner:  NLM     Status:  MEDLINE    
Retrospective review of CBC and serum chemical data from 124 horses admitted to the veterinary teaching hospital over a 9-month period (Feb 1, 1990 to Oct 31, 1990) indicated that 54 horses had echinocytosis (prevalence = 44%). In horses with echinocytosis, the most frequent diagnosis was colitis (23 horses; 43%). Odds ratios (measure of association) were calculated to determine the association of echinocytosis with specific hematologic and biochemical abnormalities. When evaluated in a multivariate model, low serum sodium concentration (< 136 mEq/L) was the only variable significantly associated with the incidence of echinocytosis. Within the group of 54 horses with echinocytosis, hyponatremia (35 horses; 65%), hypochloremia (35 horses; 65%), low total carbon dioxide concentration (35 horses; 65%), hypoosmolality (30 horses; 55%), and hypocalcemia (22 horses; 41%) were the most common biochemical abnormalities. It was concluded that hyponatremia was associated with increased incidence of echinocytosis. It was suggested that systemic electrolyte depletion might be involved in the induction of echinocyte formation.
R J Geor; E M Lund; D J Weiss
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  202     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-05-10     Completed Date:  1993-05-10     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  976-80     Citation Subset:  IM    
Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, St Paul 55108.
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MeSH Terms
Analysis of Variance
Colitis / blood,  veterinary*
Erythrocyte Count / veterinary
Erythrocytes / pathology*
Horse Diseases / blood*,  epidemiology
Multivariate Analysis
Odds Ratio
Retrospective Studies
Sodium / blood
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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