Document Detail

Ebstein's anomaly: a potential cause of misinterpretation of myocardial perfusion scintigraphy.
MedLine Citation:
PMID:  18404002     Owner:  NLM     Status:  MEDLINE    
We present the case of a 43-year-old woman with a history of Ebstein's anomaly, who was referred for a myocardial perfusion single-photon emission computed tomography (SPECT) study due to angina-like symptoms. Dilatation of the right ventricle and right atrium, apical displacement of the septal tricuspid leaflet, small left ventricle with good left ventricular and a moderate degree of tricuspid regurgitation with mild pulmonary hypertension were found on echocardiography. Myocardial SPECT perfusion imaging with [99m Tc]tetrofosmin demonstrated a large defect in the inferior septal wall in the stress study with mild partial reversibility at rest. Coronary angiography revealed normal coronary arteries. Histological studies have shown that these patients develop increased fibrosis in the left ventricular wall and ventricular septum, especially in the basal and middle region of the septum, which adjoins with the atrialized component of the right ventricle. This is in concordance with the findings of the myocardial perfusion scan in the case described.
Nikos T Kouris; Athanassios Antonopoulos; Dimitra D Kontogianni; Dimitris K Babalis
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiovascular medicine (Hagerstown, Md.)     Volume:  9     ISSN:  1558-2027     ISO Abbreviation:  J Cardiovasc Med (Hagerstown)     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-11     Completed Date:  2008-08-26     Revised Date:  2009-05-28    
Medline Journal Info:
Nlm Unique ID:  101259752     Medline TA:  J Cardiovasc Med (Hagerstown)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  498-500     Citation Subset:  IM    
Cardiology Department, Western Attica General Hospital, Greece.
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MeSH Terms
Coronary Angiography*
Coronary Disease / diagnosis
Ebstein Anomaly / radionuclide imaging*
Exercise Test
Heart / radionuclide imaging*
Tomography, Emission-Computed, Single-Photon*
Tricuspid Valve / radionuclide imaging

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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