Document Detail

Ebstein's anomaly of the left-sided tricuspid valve: pathological anatomy of the valvular malformation.
MedLine Citation:
PMID:  14740685     Owner:  NLM     Status:  MEDLINE    
The tricuspid valve is left-sided in congenitally corrected transposition of the great arteries and other cardiac malformations in which the ventricles are inverted. In an anatomical study of 20 hearts with ventricular inversion, nine were found to have Ebstein's anomaly of the left-sided tricuspid valve. These included eight with congenitally corrected transposition of the great arteries and one with a double outlet inverted right ventricle. Pathoanatomically left-sided Ebstein's anomaly differed from the classic right-sided variety in several respects: 1) the atrioventricular sulcus circumference was not increased; 2) the anterior leaflet of the valve was frequently cleft; 3) the anterior leaflet may interfere with the ventricular outflow; 4) the ventricular cavity receiving the malformed tricuspid valve was small, rather than dilated--and in congenitally corrected transposition of the great arteries, this is the systemic ventricle connected to the aorta. Significant hemodynamic dysfunction of the left-sided tricuspid valve has been reported in a high proportion of cases of congenitally corrected transposition of the great arteries, and surgical repair of the valve may be necessary. Our study suggests that surgical procedures used in classic right-sided Ebstein's anomaly, such as valve plication and annuloplasty or valve replacement with a high profile prosthesis, are not suited to the pathoanatomy of left-sided Ebstein's anomaly.
K R Anderson; G K Danielson; D C McGoon; J T Lie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  58     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1978 Sep 
Date Detail:
Created Date:  2004-01-26     Completed Date:  2004-02-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  I87-91     Citation Subset:  AIM; IM    
Department of Pathology and Anatomy, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55901, USA.
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MeSH Terms
Cardiac Surgical Procedures / methods*
Child, Preschool
Functional Laterality
Heart Defects, Congenital / pathology*,  surgery
Heart Valves / abnormalities*,  pathology*
Infant, Newborn
Tricuspid Valve / abnormalities*,  pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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