| Easy to diagnose, difficult to treat: keratosis lichenoides chronica. | |
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MedLine Citation:
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PMID: 19196302 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Keratosis lichenoides chronica (KLC) is a rare disease, with approximately 70 cases reported in the literature. The problem in this long-lasting disease is generally the treatment, not the diagnosis. In the literature, many treatments failed to show any beneficial effect. We present a 20-year-old man with KLC that was successfully treated with a combination of phototherapy, acitretin and calcipotriol ointment. The patient's lesions showed a marked improvement with this combination. To our knowledge, this is the first report of this type of combination treatment being used successfully in KLC. This approach might help reduce doses of retinoids or psoralen ultraviolet A required when these are used separately, and limit the potential toxicity of these treatments. |
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Authors:
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E Adi?en; O Erdem; S Celep?i; M A G?rer |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-12-13 |
Journal Detail:
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Title: Clinical and experimental dermatology Volume: 35 ISSN: 1365-2230 ISO Abbreviation: Clin. Exp. Dermatol. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-23 Completed Date: 2010-05-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7606847 Medline TA: Clin Exp Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 47-50 Citation Subset: IM |
Affiliation:
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Departments of Dermatology, Gazi University Faculty of Medicine, Ankara, Turkey. eozsoy@gazi.edu.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acitretin
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therapeutic use* Administration, Cutaneous Calcitriol / analogs & derivatives*, therapeutic use Chronic Disease Combined Modality Therapy / methods Dermatologic Agents / therapeutic use* Humans Keratosis / drug therapy, pathology* Lichenoid Eruptions / drug therapy, pathology* Male Phototherapy / methods* Treatment Outcome Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Dermatologic Agents; 112965-21-6/calcipotriene; 32222-06-3/Calcitriol; 55079-83-9/Acitretin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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