| Early vitamin K deficiency bleeding after maternal phenobarbital intake: management of massive intracranial haemorrhage by minimal surgical intervention. | |
| | |
MedLine Citation:
|
PMID: 9727852 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vitamin K deficiency bleeding within the first 24 h of life is caused in most cases by maternal drug intake (e.g. coumarins, anticonvulsants, tuberculostatics) during pregnancy. Haemorrhage is often life-threatening and usually not prevented by vitamin K prophylaxis at birth. We report a case of severe intracranial bleeding at birth secondary to phenobarbital-induced vitamin K deficiency and traumatic delivery. Burr hole trepanations of the skull were performed and the subdural haematoma was evacuated. Despite the severe prognosis, the infant showed an unexpected good recovery. At the age of 3 years, neurological examinations were normal as was the EEG at the age of 9 months. CT showed close to normal intracranial structures. CONCLUSION: This case report stresses the importance of antenatal vitamin K prophylaxis and the consideration of a primary Caesarean section in maternal vitamin K deficiency states and demonstrates the successful management of massive subdural haemorrhage by a limited surgical approach. |
| | |
Authors:
|
P Renzulli; P Tuchschmid; G Eich; S Fanconi; M G Schwöbel |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European journal of pediatrics Volume: 157 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1998 Aug |
Date Detail:
|
Created Date: 1998-12-14 Completed Date: 1998-12-14 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY |
Other Details:
|
Languages: eng Pagination: 663-5 Citation Subset: IM |
Affiliation:
|
Department of Paediatric Surgery, University Children's Hospital, Zurich, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anticonvulsants
/
administration & dosage,
adverse effects* Cesarean Section Epilepsy, Generalized / drug therapy* Female Hematoma, Subdural / chemically induced*, surgery Humans Infant, Newborn Phenobarbital / administration & dosage, adverse effects* Pregnancy Pregnancy Complications / drug therapy* Treatment Outcome Trephining* Vitamin K Deficiency / chemically induced*, complications, surgery |
| Chemical | |
Reg. No./Substance:
|
0/Anticonvulsants; 50-06-6/Phenobarbital |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pharmacokinetics of oral fluconazole in premature infants.
Next Document: Clinical features of unilateral multicystic renal dysplasia in children.