Document Detail

Early ventricular fibrillation in patients with acute myocardial infarction: correlation with coronary angiographic findings.
MedLine Citation:
PMID:  8458356     Owner:  NLM     Status:  MEDLINE    
To define coronary angiographic characteristics of patients experiencing early primary ventricular fibrillation (VF) in the acute phase of myocardial infarction we studied 266 consecutive patients without clinical evidence of heart failure. Twenty-six patients (group 1) experienced early (< 12 h from the onset of symptoms of myocardial infarction) primary VF whereas 240 patients (group 2) with the same clinical characteristics served as an appropriately matched cohort. All patients were catheterized before or soon after hospital discharge (1 to 8 weeks after the acute event). There was no significant difference in left ventricular ejection fraction between the two groups of patients (39.6 +/- 6% vs 36.9 +/- 8%, P = ns). Patients with early VF had a significantly greater number of diseased vessels than those without VF (3.38 +/- 1.05 vs 2.03 +/- 1.25, P < 0.001) and a higher coronary arteriographic Gensini score (29.31 +/- 4.80 vs 20.16 +/- 4.14, P < 0.001). The left anterior descending coronary artery was identified as the infarct-related vessel in 53.6% of group 1 vs 44.5% of group 2 patients (P < 0.05). The mean maximal serum creatine kinase values were not significantly different (1897 +/- 1062 vs 1426 +/- 839 IU.l-1, P = ns) between the two groups. These data indicate that patients with early primary VF in the setting of acute myocardial infarction may have more extensive coronary artery disease than similar patients without VF. A worse prognosis could be anticipated for these patients on the basis of worse coronary anatomy.(ABSTRACT TRUNCATED AT 250 WORDS)
M Kyriakidis; P Petropoulakis; A Antonopoulos; J Barbetseas; F Georgiakodis; N Aspiotis; C Kourouclis; P Toutouzas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  14     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-04-29     Completed Date:  1993-04-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  364-8     Citation Subset:  IM    
Department of Cardiology, Hippokration Hospital, University of Athens, Greece.
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MeSH Terms
Case-Control Studies
Coronary Angiography*
Coronary Disease / pathology,  physiopathology,  radiography*
Heart Catheterization
Middle Aged
Myocardial Infarction / complications*
Stroke Volume*
Time Factors
Ventricular Fibrillation / etiology,  pathology*,  physiopathology,  radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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