| Early time points perfusion imaging: Theoretical analysis of correction factors for relative cerebral blood flow estimation given local arterial input function. | |
| | |
MedLine Citation:
|
PMID: 21497658 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
If local arterial input function (AIF) could be identified, we present a theoretical approach to generate a correction factor based on local AIF for the estimation of relative cerebral blood flow (rCBF) under the framework of early time points perfusion imaging (ET). If C(t), the contrast agent bolus concentration signal time course, is used for rCBF estimation in ET, the correction factor for C(t) is the integral of its local AIF. The recipe to apply the correction factor is to divide C(t) by the integral of its local AIF to obtain the correct rCBF. By similar analysis, the correction factor for the maximum derivative (MD1) of C(t) is the maximum signal of AIF and the correction factor for the maximum second derivative (MD2) of C(t) is the maximum derivative of AIF. In the specific case of using normalized gamma-variate function as a model for AIF, the correction factor for C(t) (but not for MD1) at the time to reach the maximum derivative is relatively insensitive to the shape of the local AIF. |
| | |
Authors:
|
Kenneth K Kwong; David A Chesler |
Related Documents
:
|
20041078 - Behavior disparities towards blood donation in sikkim, india. 16756598 - Comparison of prevalence rates of microbiological markers between bone/tissue donations... 11438028 - Detection of enterovirus viraemia in blood donors. 1308488 - Rising trend of hiv infection with special reference to blood donors. 17881848 - Experience in non-conventional wastewater treatment techniques used in the czech republic. 20041078 - Behavior disparities towards blood donation in sikkim, india. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-4-8 |
Journal Detail:
|
Title: NeuroImage Volume: - ISSN: 1095-9572 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-4-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9215515 Medline TA: Neuroimage Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011. Published by Elsevier Inc. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bidirectional communication between amygdala and fusiform gyrus during facial recognition.
Next Document: Cerebrovascular hemodynamic correlates of aging in the Lou/c rat: A model of healthy aging.