Document Detail

Early social experience affects behavioral and physiological responsiveness to stressful conditions in infant rhesus macaques (Macaca mulatta).
MedLine Citation:
PMID:  21462233     Owner:  NLM     Status:  MEDLINE    
Studies on early development have demonstrated the profound effects of early social experience on the behavioral development and physiology of young rhesus macaques. Given these relationships, we hypothesized that rhesus macaques exposed to different nursery-rearing conditions may develop unique biobehavioral profiles. If this is true, the assessment of temperament may allow us to pinpoint successful rearing environments, thus improving the overall health of nonhuman primates that are raised in captive environments. We conducted biobehavioral assessments in order to examine differences in the development of infants raised under four different peer-rearing conditions (continuous pairing (CP), intermittent pairing, CP with partner rotation, and intermittent rotational pairing) and compared these animals with data from a mother-reared control group. Overall, continuous rotationally paired animals were most similar to mother-reared controls on most behavioral and temperament measures, suggesting that more socially complex rearing environments (greater number of social partners) favor a more active behavioral style. Cortisol profiles of mother-reared controls were similar to both CP groups, and these three groups had higher cortisol concentrations than the intermittent rotational-pairing group. In addition, intermittently paired infants displayed a significantly higher frequency of self-stroke behavior during a human intruder challenge, an abnormal behavior also known as floating limb which has been shown to be a precursor of self-biting. Overall, the data are consistent with the idea that social complexity in the nursery, as operationalized in our continuous rotational pairing, leads to a biobehavioral profile that is most similar to that of infants raised by their mothers in large, socially complex, cages.
Ina Rommeck; John P Capitanio; Sarah C Strand; Brenda McCowan
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2011-04-01
Journal Detail:
Title:  American journal of primatology     Volume:  73     ISSN:  1098-2345     ISO Abbreviation:  Am. J. Primatol.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-05-23     Completed Date:  2011-09-06     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  8108949     Medline TA:  Am J Primatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  692-701     Citation Subset:  IM    
Copyright Information:
© 2011 Wiley-Liss, Inc.
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MeSH Terms
Behavior, Animal*
Housing, Animal*
Hydrocortisone / blood
Macaca mulatta / blood,  physiology*
Social Behavior
Social Environment*
Grant Support
P51 OD011107/OD/NIH HHS; P51 RR000169/RR/NCRR NIH HHS; P51 RR000169-46/RR/NCRR NIH HHS; R24 OD010962/OD/NIH HHS; R24 RR019970/RR/NCRR NIH HHS; R24 RR019970-07/RR/NCRR NIH HHS; RR019970/RR/NCRR NIH HHS
Reg. No./Substance:

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