Document Detail


Early side effects after embolization of a carotid body tumor using Onyx.
MedLine Citation:
PMID:  20655684     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case of a 20-year-old woman with a carotid body tumor of Shamblin class III is reported. Ten hours after preoperative direct intralesional embolization with 20 mL Onyx (ethylene-vinyl alcohol copolymer; Micro Therapeutics, Irvine, Calif), the patient showed symptoms of Horner syndrome and deficits of the hypoglossal and glossopharyngeal nerves. Intraoperative examination 12 hours after Onyx embolization revealed a massive swelling of the hypoglossal and glossopharyngeal nerves. The patient's tongue motility and glossopharyngeal function improved after surgery, but Horner syndrome was still present. Owing to the delayed occurrence of these adverse effects, the optimal time of surgical intervention after Onyx embolization should be discussed and perhaps expedited.
Authors:
Susanne Wiegand; Ingo Kureck; Rene Chapot; Andreas M Sesterhenn; Siegfried Bien; Jochen A Werner
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-07-23
Journal Detail:
Title:  Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter     Volume:  52     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-06     Completed Date:  2010-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  742-5     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Campus Marburg, Marburg, Germany. wiegand@med.uni-marburg.de
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MeSH Terms
Descriptor/Qualifier:
Carotid Body Tumor / blood supply,  diagnosis,  therapy*
Dimethyl Sulfoxide / adverse effects*
Embolization, Therapeutic / adverse effects*
Female
Glossopharyngeal Nerve Diseases / etiology*
Head and Neck Neoplasms / blood supply,  diagnosis,  therapy*
Horner Syndrome / etiology*
Humans
Hypoglossal Nerve Diseases / etiology*
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Polyvinyls / adverse effects*
Time Factors
Treatment Outcome
Young Adult
Chemical
Reg. No./Substance:
0/Onyx copolymer; 0/Polyvinyls; 67-68-5/Dimethyl Sulfoxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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