Document Detail

Early risk factors in schizophrenia: place and season of birth.
MedLine Citation:
PMID:  19698334     Owner:  NLM     Status:  In-Data-Review    
First admission psychiatric patients born in England and Wales between 1938 and 1963, and discharged from hospitals in England and Wales between 1976 and 1986, were examined. Using logistic regression, we tested the hypothesis that the risk of shizophrenia varies by place, and season of birth. Persons born in city areas showed a 12% greater risk of schizophrenia (odds ratio 1.12; 95% confidence interval 1.06 to 1.19) than those born in non-city areas, when compared with other psychiatric patients. The increase in risk was particularly high for individuals born in city areas in winter (21%, ie odds ratio 1.21 and confidence interval 1.08 to 1.36). These findings suggest that the factor(s) responsible for the season-of-birth effect preferentially affects city born schizophrenics.
N Takei; P Sham; E Callaghan; G Glover; R Murray
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European psychiatry : the journal of the Association of European Psychiatrists     Volume:  10     ISSN:  0924-9338     ISO Abbreviation:  Eur. Psychiatry     Publication Date:  1995  
Date Detail:
Created Date:  2009-08-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111820     Medline TA:  Eur Psychiatry     Country:  France    
Other Details:
Languages:  eng     Pagination:  165-70     Citation Subset:  -    
Genetics section, Department of Psychological Medicine, King's College Hospital and Institute of Psychiatry, London SE5 8AF, UK.
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