Document Detail


Early rheumatoid-like synovial lesions in rabbits drinking cow's milk. I. Joint pathology.
MedLine Citation:
PMID:  3876289     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rheumatoid-like lesions developed in 9 of 25 (36%) Old English rabbits drinking cow's milk for 12 weeks. The incidence of lesions in male and female animals was similar. The majority of rabbits drinking cow's milk developed increased numbers of nucleated cells and raised percentages of T lymphocytes in their synovial fluids, compared to control rabbits. The cell counts and T cell percentages correlated with the severity of the histological lesions. No evidence of glomerulonephritis was observed in any of the experimental animals.
Authors:
C J Welsh; A C Hanglow; P Conn; T H Barker; R R Coombs
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International archives of allergy and applied immunology     Volume:  78     ISSN:  0020-5915     ISO Abbreviation:  Int. Arch. Allergy Appl. Immunol.     Publication Date:  1985  
Date Detail:
Created Date:  1985-10-29     Completed Date:  1985-10-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404561     Medline TA:  Int Arch Allergy Appl Immunol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  145-51     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Arthritis, Rheumatoid / etiology*
Cartilage, Articular / pathology
Cattle
Disease Models, Animal
Female
Kidney / anatomy & histology
Male
Milk / adverse effects*
Neutrophils / immunology
Plasma Cells / immunology
Rabbits
Synovial Fluid / cytology,  immunology
T-Lymphocytes / immunology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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