Document Detail

Early results of single-stage biventricular repair of severe aortic hypoplasia or atresia with ventricular septal defect and normal left ventricle.
MedLine Citation:
PMID:  16872947     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Biventricular repair of aortic atresia (or severe aortic hypoplasia) is possible in the presence of a ventricular septal defect and normal left ventricle. We considered whether primary biventricular repair was a safe alternative in all cases, even in the presence of interrupted aortic arch. METHODS: This was a retrospective analysis of patients who underwent primary biventricular repair consisting of a combination Norwood-type reconstruction of the aortic arch, baffle of the left ventricle to both semilunar roots, and conduit placement from the right ventricle to pulmonary arteries. RESULTS: Between January 1995 and January 2005, a total of 21 patients underwent primary biventricular repair at a median age of 5 days and a median weight of 3.0 kg. Aortic atresia was present in 7 and aortic stenosis in 14; 6 had interrupted aortic arch. All patients with aortic stenosis had annular diameters 3 mm or smaller. Median circulatory arrest time was 55 minutes, aortic crossclamp time was 56 minutes, and total support time was 99 minutes. In-hospital survival was 100%. Postoperative echocardiography in 19 patients demonstrated no significant outflow tract obstruction. Total stay was a median of 17 days. At midterm follow-up, there has been 1 late death, and reoperation has been necessary in 10 cases. CONCLUSION: Primary biventricular repair is a safe alternative to staged repair in all cases of aortic hypoplasia with ventricular septal defect and normal left ventricle.
Peter J Gruber; Stephanie Fuller; Kathryn M Cleaver; Ibrahim Abdullah; Stephen B Gruber; Susan C Nicolson; J William Gaynor; Gil Wernovsky; Thomas L Spray
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Publication Detail:
Type:  Journal Article     Date:  2006-06-30
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  132     ISSN:  1097-685X     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-28     Completed Date:  2006-09-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  260-3     Citation Subset:  AIM; IM    
Pediatric Cardiothoracic Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa 19104, USA.
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MeSH Terms
Aorta, Thoracic / pathology,  surgery*
Aortic Valve Stenosis / epidemiology,  surgery*
Cardiac Surgical Procedures / methods*
Cardiopulmonary Bypass
Heart Septal Defects, Ventricular / epidemiology*,  surgery*
Heart Ventricles / surgery
Hypoplastic Left Heart Syndrome / epidemiology*,  surgery*
Infant, Newborn
Length of Stay
Retrospective Studies
Suture Techniques
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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