Document Detail


Early recurrence in unipolar depression.
MedLine Citation:
PMID:  2653267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
While some advances have occurred in the maintenance treatment of unipolar depression, empirical data on recurrences of illness following the discontinuation of medication are sparse. We examined survival time during the first 18 months after discontinuation of medication in 74 patients with recurrent unipolar depression. Although demographic characteristics, clinical characteristics, and pharmacologic treatment variables failed to predict time to recurrence, continued interpersonal psychotherapy was significantly related to longer survival time.
Authors:
E Frank; D J Kupfer; J M Perel
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of general psychiatry     Volume:  46     ISSN:  0003-990X     ISO Abbreviation:  Arch. Gen. Psychiatry     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-05-31     Completed Date:  1989-05-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372435     Medline TA:  Arch Gen Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  397-400     Citation Subset:  AIM; IM    
Affiliation:
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Clinical Trials as Topic
Depressive Disorder / drug therapy,  prevention & control*,  therapy
Female
Follow-Up Studies
Humans
Imipramine / therapeutic use*
Male
Outcome and Process Assessment (Health Care)
Personality Inventory
Psychiatric Status Rating Scales
Psychotherapy*
Recurrence
Time Factors
Grant Support
ID/Acronym/Agency:
MH-29618/MH/NIMH NIH HHS; MH-30915/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
50-49-7/Imipramine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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