Document Detail

Early predictors of neurodevelopmental outcome at 12-36 months in very low-birthweight infants.
MedLine Citation:
PMID:  2288378     Owner:  NLM     Status:  MEDLINE    
We followed-up 71 preterm survivors, 36 (50.7%) females and 35 (49.3%) males, correlating the results of neurological examinations (NE) at 40 weeks of corrected gestational age (GA) and the cerebral ultrasound (US) diagnosis with the neurodevelopmental outcome at 12-36 months of life. All 34 children with normal NE at term presented adequate neurodevelopmental outcome; these subjects have a normal US scan or a scan that is pathologic for uncomplicated hemorrhage. Of the 6 children with pathologic NE, but a normal US, 3 (50%) had a normal outcome, while 2 (34%) had mild impairments and 1 (16%) grave neurodevelopmental deficits. Of the 31 subjects with pathologic NE and US, 12 (39%) showed a normal outcome, and 6 (19%) had mild and 13 (42%) grave neurodevelopmental deficits; signs of parenchymal lesions with or without periventricular hemorrhage were particularly correlated to US. We conclude that the combination of the results of NE at 40 weeks GA and brain US are useful in early neurodevelopmental prognosis in very low-birthweight infants.
G Lanzi; E Fazzi; A Gerardo; A Ometto; F Piazza; G Rondini
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain & development     Volume:  12     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  1990  
Date Detail:
Created Date:  1991-03-22     Completed Date:  1991-03-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  482-7     Citation Subset:  IM    
Department of Child Neuropsychiatry, C. Mondino Foundation, IRCCS, University of Pavia, Italy.
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MeSH Terms
Child, Preschool
Follow-Up Studies
Gestational Age
Infant, Low Birth Weight / physiology*
Infant, Newborn
Nervous System / growth & development*
Neurologic Examination

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