Document Detail

Early prediction of left ventricular systolic dysfunction in patients of asymptomatic chronic severe rheumatic mitral regurgitation using tissue Doppler and strain rate imaging.
MedLine Citation:
PMID:  22664804     Owner:  NLM     Status:  MEDLINE    
AIMS: Identification of subclinical left ventricular (LV) dysfunction in patients with rheumatic mitral regurgitation (MR) facilitates optimal surgical results and better postoperative LV function. This study is designed to assess the role of tissue Doppler and strain rate (SR) imaging in early detection of LV systolic dysfunction in patients with asymptomatic chronic severe MR.
METHODS AND RESULTS: Patients were studied under four groups. Group I: Normal subject (n = 25). Group II: Patients with chronic severe MR with ejection fraction (EF) > 60% and end-systolic dimension (ESD) ≤ 40 mm (n=23). Group III: Patients with chronic severe MR with EF ≥ 60% and ESD 41-50 mm (n = 27). Group IV: Patients with chronic severe MR with EF < 60% with any ESDs (n = 25). With decrease in EF and increase in ESD there was decrease in systolic velocity and increased in precontraction time and contraction time was noted. The tissue Doppler systolic indices between groups were statistically significant P < 0.05 and showed significant correlation value r = 0.45 between groups. Strain (S) and SR significantly decreased with decrease in EF and increase in ESD P < 0.05, r = 0.45 between different groups.
CONCLUSION: Our study showed significant correlation between tissue Doppler systolic indices and SR imaging with EF and ESD.
Manish Gunjan; Sumod Kurien; S Tyagi
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Indian heart journal     Volume:  64     ISSN:  0019-4832     ISO Abbreviation:  Indian Heart J     Publication Date:    2012 May-Jun
Date Detail:
Created Date:  2012-06-05     Completed Date:  2013-08-27     Revised Date:  2014-03-12    
Medline Journal Info:
Nlm Unique ID:  0374675     Medline TA:  Indian Heart J     Country:  India    
Other Details:
Languages:  eng     Pagination:  245-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
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MeSH Terms
Cross-Sectional Studies
Echocardiography, Doppler*
Mitral Valve Insufficiency / complications*,  ultrasonography*
Predictive Value of Tests
Rheumatic Diseases / complications*,  ultrasonography*
Stroke Volume / physiology
Ventricular Dysfunction, Left / diagnosis*,  etiology
Young Adult
Comment In:
Indian Heart J. 2012 May-Jun;64(3):249-53   [PMID:  22664805 ]

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