Document Detail

Early peristalsis following epidural analgesia during abdominal surgery in an extremely low birth weight infant.
MedLine Citation:
PMID:  17238891     Owner:  NLM     Status:  MEDLINE    
The inhibiting effect of opioids on intestinal motility is a cause of particular concern in extremely low birth weight (ELBW; birth weight <1000 g) infants with decreased peristalsis. An ELBW infant (birth weight 740 g) born after 26 + 1 week of gestation had an uneventful clinical course during the first few days of life. Sudden deterioration occurred on day 8 with metabolic acidosis, hyperglycemia and frequent apnea with secondary bradycardia. A chest X ray demonstrated the presence of air beneath the diaphragm. Intestinal perforation was suspected and the infant was taken to theater for laparotomy. For pain management, a 22 G epidural catheter was inserted via the caudal approach and threaded to a mid-thoracic level. Epidural ropivacaine was administered intraoperatively and for 48 h postoperatively. The infant was extubated on the following day. Opioids were not required or given at any stage during or after surgery. Peristalsis was present on auscultation as early as 3 h after surgery, the first stool was passed on the same day. Enteral nutrition was resumed early and tolerated well, full enteral feeding was rapidly achieved. Our case shows that the technique of caudal anesthesia is feasible in ELBW infants. We speculate that intestinal motility and establishment of full enteral feedings may be achieved earlier by epidural ropivacaine in cases of abdominal surgery in ELBW infants.
Thomas Hoehn; Martin Jetzek-Zader; Martin Blohm; Ertan Mayatepek
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  17     ISSN:  1155-5645     ISO Abbreviation:  Paediatr Anaesth     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-22     Completed Date:  2007-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  France    
Other Details:
Languages:  eng     Pagination:  176-9     Citation Subset:  IM    
Neonatology and Pediatric Intensive Care Medicine, Department of General Pediatrics, Heinrich-Heine-Universiry, Dusseldorf, Germany.
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MeSH Terms
Abdomen / surgery*
Acidosis / etiology
Amides / administration & dosage,  adverse effects,  therapeutic use
Analgesia, Epidural / adverse effects*
Anesthetics, Local / administration & dosage,  adverse effects,  therapeutic use
Apnea / etiology
Bradycardia / etiology
Enteral Nutrition / methods
Gastrointestinal Motility / drug effects
Hyperglycemia / etiology
Infant, Extremely Low Birth Weight*
Infant, Newborn
Intestinal Perforation / complications,  surgery*
Intubation, Intratracheal
Pain / prevention & control
Peristalsis / drug effects*
Time Factors
Reg. No./Substance:
0/Amides; 0/Anesthetics, Local; 84057-95-4/ropivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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