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Early onset pregnancy-induced hypertension/eclampsia in Benin City, Nigeria.
MedLine Citation:
PMID:  21220851     Owner:  NLM     Status:  In-Data-Review    
Context: Pregnancy - induced hypertension/eclampsia is a major cause of maternal and perinatal morbidity and mortality in Nigeria. There have been very few studies focused on early onset pregnancy induced hypertension/eclampsia in Nigerian women Objectives: To determine the incidence, clinical features and outcome of cases of early onset pregnancy-induced hypertension /eclampsia in a Nigerian tertiary hospital, and compare maternofetal outcome in early and late onset disease. Methods : A retrospective study of all cases of early onset pregnancy induced hypertension/eclampsia seen over a five-year period in a tertiary hospital. Main outcome measures : Severity of disease, rates of induction of labour, caesarean section rate, maternal mortality, abruptio placenta, still births, severe birth asphyxia and early neonatal deaths. Results : Early onset pregnancy induced hypertension/eclampsia contributed 6.3% of all cases of hypertensive disorders in pregnancy with an incidence of 1:141 deliveries. Most cases presented at between 28-32 weeks gestation (78.3%) The disease was severe at presentation or rapidly progressive in 39 cases (84.8%) leading to delivery within 72 hours of presentation. Caesarean section was the mode of delivery in 58.7% of cases. The perinatal survival rate was 34.0%. Early onset pregnancy induced hypertension was associated with significantly higher risk of presenting with eclampsia, having induction of labour and worse perinatal outcome than late onset disease. Conclusion : Most cases of early onset pregnancy induced hypertension in the study population presented with severe and rapidly progressive disease and were associated with significantly higher risk of obstetric intervention and worse perinatal outcome than late onset disease.
P N Ebeigbe; M E Aziken
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nigerian journal of clinical practice     Volume:  13     ISSN:  1119-3077     ISO Abbreviation:  Niger J Clin Pract     Publication Date:    2010 Oct-Dec
Date Detail:
Created Date:  2011-01-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101150032     Medline TA:  Niger J Clin Pract     Country:  India    
Other Details:
Languages:  eng     Pagination:  388-93     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, College of Health Sciences, Delta State University, Abraka, Nigeria.
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