Document Detail


Early onset of nephrotic syndrome after treatment with D-penicillamine in a patient with Wilson's disease.
MedLine Citation:
PMID:  9860423     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Wilson's disease responds to a variety of treatments including D-penicillamine and trientene. Nephrotic syndrome is a late complication of D-penicillamine treatment. We report a pediatric patient with Wilson's disease who developed nephrotic syndrome 2 wk after beginning D-penicillamine. His nephrosis resolved and his disease is quiescent with trientene treatment.
Authors:
C G Siafakas; M M Jonas; S Alexander; J Herrin; G T Furuta
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  93     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-01-08     Completed Date:  1999-01-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2544-6     Citation Subset:  IM    
Affiliation:
The Combined Program in Pediatric Gastroenterology and Nutrition, The Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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MeSH Terms
Descriptor/Qualifier:
Chelating Agents / adverse effects*,  therapeutic use
Child
Hepatolenticular Degeneration / drug therapy*
Humans
Male
Nephrotic Syndrome / chemically induced*
Penicillamine / adverse effects*,  therapeutic use
Retreatment
Time Factors
Triethylenetetramine / therapeutic use
Chemical
Reg. No./Substance:
0/Chelating Agents; 112-24-3/Triethylenetetramine; 52-67-5/Penicillamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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