Document Detail


Early onset myasthenia gravis with atypical features.
MedLine Citation:
PMID:  18769095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 14 year old boy with atypical myasthenia gravis is reported. The interesting features of the case were the onset in first decade with progressive weakness of limb muscles simulating limb girdle myopathy, presence of bilateral symmetrical non fluctuating external ophthalmoplegia with ptosis and the absence of diplopia. Differential response to choline esterase inhibitors was clinically apparent. In contrast to excellent improvement in limb weakness with choline esterase inhibitors, there was no improvement in external ophthalmoplegia or ptosis. The possibilities are discussed and literature is reviewed.
Authors:
P Agarwal; U Chapagain; K R Deewan; P V Rana
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Kathmandu University medical journal (KUMJ)     Volume:  6     ISSN:  1812-2078     ISO Abbreviation:  Kathmandu Univ Med J (KUMJ)     Publication Date:    2008 Apr-Jun
Date Detail:
Created Date:  2008-09-04     Completed Date:  2010-03-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101215359     Medline TA:  Kathmandu Univ Med J (KUMJ)     Country:  Nepal    
Other Details:
Languages:  eng     Pagination:  231-4     Citation Subset:  IM    
Affiliation:
College of Medical Sciences , Bharatpur, Nepal.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Cholinesterase Inhibitors / therapeutic use*
Humans
Male
Myasthenia Gravis / complications,  diagnosis*,  drug therapy*
Ophthalmoplegia / etiology
Pyridostigmine Bromide / therapeutic use*
Chemical
Reg. No./Substance:
0/Cholinesterase Inhibitors; 101-26-8/Pyridostigmine Bromide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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