Document Detail

Early onset group B streptococcal disease: clinical, roentgenographic, and pathologic features.
MedLine Citation:
PMID:  781201     Owner:  NLM     Status:  MEDLINE    
Thirty-one neonates with early onset of serious group B streptococcal infections were observed in a four-year period. The mortality was 52%. Premature infants with clinical signs of respiratory distress syndrome were at highest risk of death; clinical signs of RDS were typical until apnea, shock, respiratory failure, and worsening of the radiographic pattern unexpectedly intervened. Pathologic material from infants with radiographic evidence either of RDS or of pneumonia showed both typical hyaline membrane disease and pneumonia in most instances. Factors which may be helpful in recognizing premature infants at risk for GBS disease in the much larger group of premature infants with uncomplicated RDS include: history of artificial, premature, or prolonged rupture of membranes; localized pulmonary infiltrates on chest roentgenogram; low absolute neutrophil count; and an unusually rapid progression of RDS.
J H Vollman; W L Smith; E T Ballard; I J Light
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  89     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1976 Aug 
Date Detail:
Created Date:  1976-09-25     Completed Date:  1976-09-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  199-203     Citation Subset:  AIM; IM    
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MeSH Terms
Hyaline Membrane Disease / pathology
Infant, Newborn
Infant, Newborn, Diseases / radiography*
Infant, Premature, Diseases / radiography*
Lung / pathology
Pneumonia / pathology
Respiratory Distress Syndrome, Newborn / radiography
Streptococcal Infections / pathology,  radiography*
Streptococcus agalactiae / isolation & purification*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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