| Early-onset drug use and risk for drug dependence problems. | |
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MedLine Citation:
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PMID: 19022584 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is substantial evidence that alcohol, tobacco, and cannabis dependence problems surface more quickly when use of these drugs starts before adulthood, but the evidence based on other internationally regulated drugs (e.g., cocaine) is meager. With focus on an interval of up to 24 months following first drug use, we examine drug-specific and age-specific variation in profiles of early-emerging clinical features associated with drug dependence. Based upon the United States National Surveys on Drug Use and Health (NSDUH) conducted in 2000-2002, the risk of experiencing drug dependence problems was robustly greater for adolescent recent-onset users of cocaine, psychostimulant drugs other than cocaine, analgesics, anxiolytic medicines, inhalants drugs, and cannabis, as compared to adult recent-onset users (odds ratio=1.5-4.3, p<0.05). This was not the case for the NSDUH hallucinogens group (e.g., LSD). The adolescent onset associated excess risk was not constant across all clinical features. Our evidence suggests promoting earlier detection and interventions, as well as greater parent and peer awareness of drug dependence clinical features that may develop early among young people who have just started using drugs. |
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Authors:
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Chuan-Yu Chen; Carla L Storr; James C Anthony |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2008-11-01 |
Journal Detail:
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Title: Addictive behaviors Volume: 34 ISSN: 1873-6327 ISO Abbreviation: Addict Behav Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-01-12 Completed Date: 2009-09-21 Revised Date: 2011-09-26 |
Medline Journal Info:
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Nlm Unique ID: 7603486 Medline TA: Addict Behav Country: England |
Other Details:
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Languages: eng Pagination: 319-22 Citation Subset: IM |
Affiliation:
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National Health Research Institutes, Division of Mental Health and Substance Abuse Research, 35 Keyan Road, Zhunan, Miaoli County 350, Taiwan. cychen@nhri.org.tw |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Factors Female Health Knowledge, Attitudes, Practice Humans Male Risk Factors Substance-Related Disorders / epidemiology* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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K05 DA015799-06/DA/NIDA NIH HHS; K05DA015799/DA/NIDA NIH HHS; R01 DA009897-04/DA/NIDA NIH HHS; R01 DA016323-03/DA/NIDA NIH HHS; R01DA016323/DA/NIDA NIH HHS; R01DA09897/DA/NIDA NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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