Document Detail

Early-onset bacterial infection in Brazilian neonates with respiratory distress: a hospital-based study.
MedLine Citation:
PMID:  14984162     Owner:  NLM     Status:  MEDLINE    
We investigated infants with respiratory distress within 4 days of birth whose mothers had not received antibiotic prophylaxis to evaluate the frequency and etiology of bacterial infection and associated risk factors. The study was conducted on 261 infants suffering respiratory distress admitted to a Brazilian neonatal intensive care unit, 94 per cent of whom were born prematurely. Gestational and delivery history; bacteriological cultures of blood, cerebrospinal fluid, tracheal aspirates and urine; complete and differential blood counts; a urinary group B streptococcal latex antigen test; and a chest radiograph were analysed. Indications of infection were found in 38.7 per cent and confirmed in 11.9 per cent of the neonates. Gram-positive (70.9 per cent) and gram-negative bacteria (29.1 per cent) were found in 31 cases of confirmed early bacteremia. Group B Streptococcus was the predominant causative agent (19.4 per cent) in infants exhibiting confirmed infection. Culture-proven infection was more frequent among infants delivered vaginally (adjusted OR = 2.53, p = 0.05) or born to mothers with signs of intra-amniotic infection (adjusted OR = 2.83, p = 0.04). Preventive measures against early bacterial infection in preterm infants from this population are strongly warranted.
Marisa M Mussi-Pinhata; Rivianny A Nobre; Francisco Eulógio Martinez; Salim Moyses Jorge; Maria Lúcia Silveira Ferlin; Arthur Lopes Gonçalves
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  50     ISSN:  0142-6338     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-26     Completed Date:  2004-03-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  6-11     Citation Subset:  IM    
Department of Pediatrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
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MeSH Terms
Bacterial Infections / complications,  epidemiology*
Brazil / epidemiology
Infant, Newborn
Infant, Premature / blood
Infectious Disease Transmission, Vertical
Intensive Care Units, Neonatal
Logistic Models
Respiratory Tract Infections / epidemiology*,  microbiology
Risk Factors

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