Document Detail


Early myocardial involvement in collagen diseases. An endomyocardial biopsy study
MedLine Citation:
PMID:  1961438     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Endomyocardial biopsy was performed in three patients affected by systemic connectivitis (one case of systemic lupus erythematosus--SLE--, one of scleroderma and one of dermatomyositis). The analysis of the specimens revealed the presence of fibrosis and microvascular lesions (these latter only in SLE). Immunofluorescence showed in SLE and scleroderma perivascular IgG or perisarcolemmal IgM deposits respectively. Despite the scarcity of cardiac signs and symptoms, cardiac involvement can be early and frequent in connectivitis. The immune pathogenesis of the cardiac lesions seems to be possible because of the presence of immunocomplexes in the myocardium.
Authors:
C Tamburino; E Salomone; R Di Paola; G Bruno; G Russo; S Tolaro; R Foti; C E Fiore
Publication Detail:
Type:  Case Reports; English Abstract; Journal Article    
Journal Detail:
Title:  Minerva cardioangiologica     Volume:  39     ISSN:  0026-4725     ISO Abbreviation:  Minerva Cardioangiol     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1992-01-06     Completed Date:  1992-01-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0400725     Medline TA:  Minerva Cardioangiol     Country:  ITALY    
Other Details:
Languages:  ita     Pagination:  209-12     Citation Subset:  IM    
Affiliation:
Istituti di Clinica Medica, L. Condorelli, Università di Catania.
Vernacular Title:
Precoce coinvolgimento miocardico nelle collagenopatie. Studio con biopsia endomiocardica.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Biopsy
Child
Collagen Diseases / pathology*
Dermatomyositis / pathology
Endocardium / pathology
Female
Humans
Lupus Erythematosus, Systemic / pathology
Middle Aged
Myocardium / pathology*
Scleroderma, Systemic / pathology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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