Document Detail

Early mobilisation for patients following acute myocardiac infarction: a systematic review and meta-analysis of experimental studies.
MedLine Citation:
PMID:  19411076     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the impact of early mobilisation (EM) on total mortality and non-fatal re-infarction after acute myocardial infarction (AMI). DESIGN: Systematic review and meta-analysis. DATA SOURCES: MEDLINE, CINAHL, HealthStar, EMBASE, the Cochrane Library Controlled Trials Registry and experts. METHODS: Target studies included published and unpublished experimental, controlled studies in any language comparing AMI patients allocated to any in-hospital early mobilisation or a control/standard treatment. Two reviewers independently assessed study eligibility and quality and performed data extraction. We calculated relative risks (RRs) and 95% confidence intervals (CIs) using the random-effects model. OUTCOMES: All-cause mortality or re-infarction up to 1-year post-AMI. RESULTS: Out of 385 potentially relevant studies, 14 met our eligibility criteria (13 published before 1983). There were 149 deaths (9.3% of 1607) and 82 non-fatal re-infarctions (5.2% of 1580) among post-AMI patients receiving EM, compared with 179 deaths (11.6% of 1541) and 80 non-fatal re-infarctions (5.3% of 1518) among AMI patients receiving control treatment (RR=0.85, 95% CI 0.68, 1.05 and RR=1.02, 95% CI 0.75, 1.39 respectively). CONCLUSION: Our meta-analysis demonstrated a trend towards decreased mortality with EM after AMI. However, there is uncertainty about early mobilisation and more research should be developed having into account all kind of differences among patients receiving treatment after AMI worldwide.
Olga L Cortes; Juan C Villar; P J Devereaux; Alba DiCenso
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-05-02
Journal Detail:
Title:  International journal of nursing studies     Volume:  46     ISSN:  1873-491X     ISO Abbreviation:  Int J Nurs Stud     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-09-14     Completed Date:  2009-11-16     Revised Date:  2010-05-04    
Medline Journal Info:
Nlm Unique ID:  0400675     Medline TA:  Int J Nurs Stud     Country:  England    
Other Details:
Languages:  eng     Pagination:  1496-504     Citation Subset:  IM; N    
School of Nursing, Universidad Industrial de Santander, Carrera 32 # 29-31, Room 5 floor, Bucaramanga, Santander, Colombia.
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MeSH Terms
Myocardial Infarction / physiopathology*
Comment In:
Evid Based Med. 2010 Apr;15(2):47-8   [PMID:  20436120 ]
Evid Based Nurs. 2010 Apr;13(2):39   [PMID:  20436139 ]
Int J Nurs Stud. 2010 Feb;47(2):263   [PMID:  19846092 ]

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