| Early mitral filling/diastolic mitral annular velocity ratio is not a reliable predictor of left ventricular filling pressure in the setting of severe mitral regurgitation. | |
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MedLine Citation:
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PMID: 16423674 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The early mitral filling velocity (E)/early diastolic mitral annular velocity (E') ratio is increasingly being used as a simplified approach to estimate left ventricular (LV) filling pressure. The validity of applying this Doppler parameter to patients with severe mitral regurgitation is unknown. We retrospectively identified 20 patients in sinus rhythm who had LV end-diastolic pressure (LVEDP) invasively measured within 72 hours of a full echocardiogram including diastolic parameters. We observed a poor correlation between E/E' ratio and LVEDP in these patients (r = -0.07, P = not significant). Previously described E/E' cut-off values did not accurately identify patients with low, intermediate, and high LVEDP. Of the diastolic parameters measured, the most significant correlation with LVEDP was found with mitral deceleration time (r = -0.66, P = .002) and systolic/diastolic peak velocity ratio (r = -0.52, P = .02). We conclude that E/E' ratio is not reliable in predicting LV filling pressure in the setting of severe mitral regurgitation, and that in these cases mitral deceleration time or systolic/diastolic peak velocity ratio may be better indicators of LVEDP. |
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Authors:
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Jeffrey J Olson; Salvatore P Costa; Christine E Young; Robert T Palac |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 19 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2006-01-20 Completed Date: 2006-05-02 Revised Date: 2007-11-02 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 83-7 Citation Subset: IM |
Affiliation:
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Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Pressure Echocardiography / methods* Female Humans Image Interpretation, Computer-Assisted / methods* Male Mitral Valve / ultrasonography* Mitral Valve Insufficiency / complications, ultrasonography* Reproducibility of Results Retrospective Studies Sensitivity and Specificity Severity of Illness Index* Stroke Volume Ventricular Dysfunction, Left / etiology, ultrasonography* |
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