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Early localization of bronchogenic carcinoma.
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MedLine Citation:
PMID:  18493345     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The performance of a fluorescence imaging device was compared with conventional white-light bronchoscopy in 100 patients with lung cancer, 46 patients with resected stage I non-small cell lung cancer, 10 patients with head and neck cancer, and 67 volunteers who had smoked at least 1 pack of cigarettes per day for 25 years or more. Using differences in tissue autofluorescence between premalignant, malignant, and normal tissues, fluorescence bronchoscopy was found to detect significantly more areas with moderate/severe dysplasia or carcinoma in situ than conventional white-light bronchoscopy with a similar specificity. Multiple foci of dysplasia or cancer were found in 13-24% of these individuals. Fluorescence bronchoscopy may be an important adjunct to conventional bronchoscopic examination to improve our ability to detect and localize premalignant and early lung cancer lesions.
Authors:
S Lam; C Macaulay; J C Leriche; N Ikeda; B Palcic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diagnostic and therapeutic endoscopy     Volume:  1     ISSN:  1070-3608     ISO Abbreviation:  Diagn Ther Endosc     Publication Date:  1994  
Date Detail:
Created Date:  2008-05-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9502019     Medline TA:  Diagn Ther Endosc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  -    
Affiliation:
Cancer Imaging British Columbia Cancer Research Centre and The University of British Columbia Vancouver B.C. V5Z 1L3 Canada.
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Journal Information
Journal ID (nlm-ta): Diagn Ther Endosc
ISSN: 1070-3608
ISSN: 1029-0516
Publisher: Hindawi Publishing Corporation
Article Information
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Copyright ? 1994 Hindawi Publishing Corporation.
open-access: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received Day: 4 Month: 4 Year: 1994
Accepted Day: 20 Month: 5 Year: 1994
Print publication date: Year: 1994
Volume: 1 Issue: 2
First Page: 75 Last Page: 78
ID: 2362470
PubMed Id: 18493345
Publisher Item Identifier: S1070360894000159
DOI: 10.1155/DTE.1.75

Early Localization of Bronchogenic Carcinoma
S. Lam14
C. Macaulay1
J. C. Leriche2
N. Ikeda3
B. Palcic1
1Cancer ImagingBritish Columbia Cancer Research Centre and The University of British ColumbiaVancouverB.C.V5Z 1L3Canada
2Laboratory MedicineBritish Columbia Cancer AgencyVancouverB.C.V5Z 4E6Canada
3Department of SurgeryTokyo Medical College HospitalTokyoJapan
4Cancer ImagingBritish Columbia Cancer Research Centre601 West 10th AvenueVancouverB.C.V5Z 1L3Canada


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