Document Detail


Early-life trauma is associated with rapid eye movement sleep fragmentation among military veterans.
MedLine Citation:
PMID:  22266135     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The role of sleep in the relations between early-life trauma and the development of adverse psychological trajectories is relatively unknown and was the primary aim of the present study. Military veterans were evaluated for posttraumatic stress disorder, combat exposure, trauma history, sleep quality, disruptive nocturnal behaviors, and a subsample completed overnight polysomnography that yielded objectively measured sleep parameters. When relevant variables were controlled, increased earlier-life traumatic event exposure was associated with increased rapid-eye-movement sleep (REMs) fragmentation, and increased REMs fragmentation was associated with increased later-life disruptive nocturnal behaviors. REMs fragmentation carried an indirect relation between earlier-life trauma and later-life disruptive nocturnal behaviors. Objectively measured sleep parameters were used to describe REMs fragmentation physiology. The current findings elucidate the important role that earlier-life trauma exposure may have in the development of REM sleep physiology, and how this altered sleep physiology may have dynamic influences on subsequent posttraumatic stress symptoms in adulthood.
Authors:
Salvatore P Insana; David J Kolko; Anne Germain
Related Documents :
15304995 - Aliphatic alcohol and iridoid glycosides from asystasia intrusa.
22197695 - On-off intermittency of thalamo-cortical oscillations in the electroencephalogram of ra...
22215925 - The effects of stimulus degradation after 48 hours of total sleep deprivation.
22043125 - Antagonizing corticotropin-releasing factor in the central nucleus of the amygdala atte...
20305505 - Ultrasonic bone removal versus high-speed burring for lateral orbital decompression: co...
10659255 - The effects of a rider's mass on ground reaction forces and fetlock kinematics at the t...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-01-18
Journal Detail:
Title:  Biological psychology     Volume:  89     ISSN:  1873-6246     ISO Abbreviation:  Biol Psychol     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-12     Completed Date:  2012-07-02     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  0375566     Medline TA:  Biol Psychol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  570-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
Affiliation:
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Disease Progression
Female
Humans
Male
Middle Aged
Polysomnography
Psychiatric Status Rating Scales
Questionnaires
Sleep Deprivation / etiology*
Sleep, REM / physiology*
Stress Disorders, Traumatic / classification,  complications*
Time Factors
Veterans
Grant Support
ID/Acronym/Agency:
PR054093/PR/OCPHP CDC HHS; R21 MH-083035-02/MH/NIMH NIH HHS; R21 MH083035-02/MH/NIMH NIH HHS; R34 MH-080696-03/MH/NIMH NIH HHS; R34 MH080696-03/MH/NIMH NIH HHS; T32 HL-082610-04/HL/NHLBI NIH HHS; T32 HL082610-05/HL/NHLBI NIH HHS; UL1 RR024153/RR/NCRR NIH HHS; UL1 RR024153-05/RR/NCRR NIH HHS; UL1RR024153/RR/NCRR NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Increasing children's consumption of fruit and vegetables: Does the type of exposure matter?
Next Document:  Mannose-6-phosphate pathway: A review on its role in lysosomal function and dysfunction.