Document Detail


Early life, current socioeconomic position and serum lipids in young adulthood of participants in a cohort study initiated in 1978/1979.
MedLine Citation:
PMID:  17713661     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The association between socioeconomic position (SEP) and serum lipids has been little studied and the results have been controversial. A total of 2063 young adults born in 1978/79 were evaluated at 23-25 years of age in the fourth follow-up of a cohort study carried out in Ribeirão Preto, SP, Brazil, corresponding to 31.8% of the original sample. Total serum cholesterol (TC), triglycerides, high-density cholesterol (HDL cholesterol) and low-density cholesterol (LDL cholesterol) were analyzed according to SEP at birth and during young adulthood. SEP was classified into tertiles of family income and a cumulative score of socioeconomic disadvantage was created. TC was 11.85 mg/100 mL lower among men of lower SEP in childhood (P < 0.01) but no difference was found in women, whereas it was 8.46 lower among men (P < 0.01) and 8.21 lower among women of lower SEP in adulthood (P < 0.05). Individuals of lower SEP had lower LDL and HDL cholesterol, with small differences between sexes and between the two times in life. There was no association between SEP and triglyceride levels. After adjustment of income at one time point in relation to the other, some associations lost significance. The greater the socioeconomic disadvantage accumulated along life, the lower the levels of TC, LDL and HDL cholesterol (P < 0.05). The socioeconomic gradient of TC and LDL cholesterol was inverse, representing a lower cardiovascular risk for individuals of lower SEP, while the socioeconomic gradient of HDL cholesterol indicated a lower cardiovascular risk for individuals of higher SEP.
Authors:
F P Figueiredo; A A M Silva; H Bettiol; M A Barbieri; R F L Batista; F Lamy Filho; R A Silva; V M F Aragão
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-09-10
Journal Detail:
Title:  Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]     Volume:  40     ISSN:  0100-879X     ISO Abbreviation:  Braz. J. Med. Biol. Res.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-18     Completed Date:  2008-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8112917     Medline TA:  Braz J Med Biol Res     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  1267-76     Citation Subset:  IM    
Affiliation:
Departamento de Saúde Pública, Universidade Federal do MaranhãoSão Luís, MA, Brasil.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brazil / epidemiology
Cardiovascular Diseases / epidemiology,  etiology
Child
Cholesterol / blood*
Epidemiologic Methods
Female
Humans
Male
Social Class*
Triglycerides / blood*
Chemical
Reg. No./Substance:
0/Triglycerides; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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