Document Detail


Early-life conditions and age at first pregnancy in British women.
MedLine Citation:
PMID:  21068037     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is growing evidence that the reproductive schedules of female mammals can be affected by conditions experienced during early development, with low parental investment leading to accelerated life-history strategies in the offspring. In humans, the relationships between early-life conditions and timing of puberty are well studied, but much less attention has been paid to reproductive behaviour. Here, we investigate associations between early-life conditions and age at first pregnancy (AFP) in a large, longitudinally studied cohort of British women (n = 4553). Low birthweight for gestational age, short duration of breastfeeding, separation from mother in childhood, frequent family residential moves and lack of paternal involvement are all independently associated with earlier first pregnancy. Apart from that of birthweight, the effects are robust to adjustment for family socioeconomic position (SEP) and the cohort member's mother's age at her birth. The association between childhood SEP and AFP is partially mediated by early-life conditions, and the association between early-life conditions and AFP is partially mediated by emotional and behavioural problems in childhood. The overall relationship between early-life adversities and AFP appears to be approximately additive.
Authors:
Daniel Nettle; David A Coall; Thomas E Dickins
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Publication Detail:
Type:  Journal Article     Date:  2010-11-10
Journal Detail:
Title:  Proceedings. Biological sciences / The Royal Society     Volume:  278     ISSN:  1471-2954     ISO Abbreviation:  Proc. Biol. Sci.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-04-21     Completed Date:  2011-08-12     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  101245157     Medline TA:  Proc Biol Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  1721-7     Citation Subset:  IM    
Affiliation:
Institute of Neuroscience, Newcastle University, Newcastle Upon Tyne, UK. daniel.nettle@ncl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Affective Symptoms
Female
Humans
Longitudinal Studies
Maternal Age*
Parent-Child Relations*
Pregnancy
Reproductive Behavior*
Social Environment*
Socioeconomic Factors
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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