| Early intervention: which patients and how early? | |
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MedLine Citation:
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PMID: 18611365 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite advances in preventive therapy, acute coronary syndromes (ACS) remain a significant cause of morbidity and mortality. Patient risk varies widely along a spectrum from unstable angina to ST-segment elevation myocardial infarctions (STEMIs) and can be estimated using risk prediction algorithms. Estimated risk is useful to select therapeutic options ranging from aggressive medical therapy for patients at low risk to revascularization for high-risk patients in whom bypass or percutaneous coronary intervention (PCI) is feasible. Appropriate timing of an invasive strategy is crucial, with early intervention maximally benefiting the highest-risk patients. Facilitated PCI's role in patients who present with STEMI and the most appropriate timing of interventional therapy in patients at moderate risk after a non-ST-elevation ACS remain the subject of ongoing debate. |
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Authors:
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J Matthew Brennan; John L Petersen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current cardiology reports Volume: 10 ISSN: 1534-3170 ISO Abbreviation: Curr Cardiol Rep Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-07-09 Completed Date: 2008-10-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888969 Medline TA: Curr Cardiol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 303-11 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC 27705, USA. brenn009@mc.duke.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome
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drug therapy,
physiopathology,
surgery,
therapy* Algorithms Angioplasty, Transluminal, Percutaneous Coronary* Coronary Artery Bypass* Fibrinolytic Agents / therapeutic use Humans Myocardial Revascularization Platelet Aggregation Inhibitors / therapeutic use Predictive Value of Tests Risk Assessment Risk Factors Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; 0/Platelet Aggregation Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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