| Early and innovative interventions for severe sepsis and septic shock: taking advantage of a window of opportunity. | |
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MedLine Citation:
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PMID: 16247103 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The pathogenic, diagnostic and therapeutic landscape of sepsis is no longer confined to the intensive care unit: many patients from other portals of entry to care, both outside and within the hospital, progress to severe disease. Approaches that have led to improved outcomes with other diseases (e.g., acute myocardial infarction, stroke and trauma) can now be similarly applied to sepsis. Improved understanding of the pathogenesis of severe sepsis and septic shock has led to the development of new therapies that place importance on early identification and aggressive management. This review emphasizes approaches to the early recognition, diagnosis and therapeutic management of sepsis, giving the clinician the most contemporary and practical approaches with which to treat these patients. |
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Authors:
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Emanuel P Rivers; Lauralyn McIntyre; David C Morro; Kandis K Rivers |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne Volume: 173 ISSN: 1488-2329 ISO Abbreviation: CMAJ Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-10-25 Completed Date: 2005-11-15 Revised Date: 2010-09-21 |
Medline Journal Info:
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Nlm Unique ID: 9711805 Medline TA: CMAJ Country: Canada |
Other Details:
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Languages: eng Pagination: 1054-65 Citation Subset: AIM; IM |
Affiliation:
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Department of Emergency Medicine, Henry Ford Hospital, Detroit, Mich, USA. erivers1@hfhs.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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therapeutic use Cell Hypoxia Diagnosis, Differential Disease Progression Fluid Therapy Humans Intensive Care Units Microcirculation Oxygen / metabolism Risk Factors Sepsis / diagnosis, physiopathology, prevention & control*, therapy Shock, Septic / diagnosis, physiopathology, prevention & control*, therapy Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 7782-44-7/Oxygen |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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