| Early glucose normalization does not improve outcome in the critically ill trauma population. | |
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MedLine Citation:
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PMID: 17879682 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Strict control of serum glucose in critically ill patients decreases morbidity and mortality. The objective of this study was to evaluate the effect of early normalization of glucose in our burn and trauma intensive care unit. From January 2002 to June 2005, 290 patients were admitted with serum glucose 150 mg/dL or greater and 319 patients with serum glucose less than 150 mg/dL. The patients with hyperglycemia were more severely injured and more often required operative intervention within the first 48 hours. The patients with hyperglycemia were at increased risk for infection and mortality. Of those 290 patients in the hyperglycemic cohort, 125 patients had early normalization of serum glucose, whereas 165 patients required more than 24 hours to normalize. The early normalization cohort was younger in mean age than the late group, but these 2 groups were similar in injury severity. Correspondingly, there was no difference in the rate of infection. Although hyperglycemia on admission appears to correlate with a worse outcome, early glucose normalization did not affect morbidity and mortality in our critically ill population. |
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Authors:
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Susanna Shin; Rebecca C Britt; Scott F Reed; Jay Collins; Leonard J Weireter; L D Britt |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American surgeon Volume: 73 ISSN: 0003-1348 ISO Abbreviation: Am Surg Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-09-20 Completed Date: 2007-10-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370522 Medline TA: Am Surg Country: United States |
Other Details:
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Languages: eng Pagination: 769-72; discussion 772 Citation Subset: IM |
Affiliation:
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Department of Surgery, Eastern Virginia Medical School, Norfolk, Virginia, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Aged, 80 and over Biological Markers / blood Blood Glucose / metabolism* Critical Illness* Female Follow-Up Studies Humans Hyperglycemia / blood*, etiology, mortality Male Middle Aged Prognosis Retrospective Studies Risk Factors Survival Rate / trends Trauma Severity Indices Virginia / epidemiology Wounds and Injuries / blood*, complications, mortality |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Blood Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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