| Early fetal growth and development in mice chronically exposed to ethanol during gestation. | |
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MedLine Citation:
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PMID: 3623189 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of maternal alcohol consumption on fetal growth and development during mid-gestation was investigated in Swiss white mice. As early as day 12 of gestation alcohol-exposed fetuses are retarded in both weight and length and remain retarded by about 0.5 to 1 day through day 16, when the experiment was terminated. From day 12 to day 16 alcohol-exposed fetuses were retarded in morphological development by about one half day, compared to controls not exposed to alcohol. Palate development began later in alcohol-exposed fetuses and was not complete in most fetuses until about 15 days 18 hours, whereas fusion was complete in most control fetuses by 15 days 0 hours. No evidence for an effect of uterine position on palate development was observed, either in control or alcohol-exposed fetuses. The manner in which alcohol consumption may affect fetal growth and development is discussed in light of these results. |
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Authors:
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M Lee |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Growth Volume: 51 ISSN: 0017-4793 ISO Abbreviation: Growth Publication Date: 1987 |
Date Detail:
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Created Date: 1987-10-22 Completed Date: 1987-10-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0205044 Medline TA: Growth Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 146-53 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Height / drug effects Body Weight / drug effects Embryonic and Fetal Development / drug effects* Ethanol / pharmacology, toxicity* Female Fetal Growth Retardation / chemically induced* Gestational Age Maternal-Fetal Exchange* Mice Palate / drug effects, embryology Pregnancy |
| Chemical | |
Reg. No./Substance:
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64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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