Document Detail

Early fetal echocardiography--a reliable prenatal diagnosis tool.
MedLine Citation:
PMID:  16157147     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study was undertaken to evaluate the feasibility and to report the detection rate of cardiac anomalies with fetal echocardiography before 16 weeks' gestation. STUDY DESIGN: This is a retrospective and prospective study of 160 early fetal echocardiograms. The mean gestational age was 13.5 weeks' gestation (range 11-15+6). All women had a repeat echocardiogram at 18 weeks' gestation and pregnancy outcome was obtained. RESULTS: In all cases, a cardiac 4-chamber view was obtained. The atrioventricular valves were accurately seen in 154 (96%) cases; the ascending aorta and main pulmonary artery were visualized in 152 cases (95%). Overall, a satisfactory cardiac examination was feasible in 152 of cases (95%). There were 20 cardiac defects in this cohort (12.5%), 14 showed abnormalities at the time of the early ultrasound, whereas 6 were reported as normal. The sensitivity of early fetal echocardiography in this high-risk population was 70%, specificity 98%, positive predictive value 87.5%, and negative predictive value 96%. CONCLUSION: The fetal heart can be examined early in pregnancy and a significant proportion of major cardiac defects identified.
Fionnuala M McAuliffe; Jean Trines; Lynne E Nield; David Chitayat; Edgar Jaeggi; Lisa K Hornberger
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  193     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-13     Completed Date:  2005-10-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1253-9     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Canada.
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MeSH Terms
Feasibility Studies
Fetal Diseases / ultrasonography*
Gestational Age
Heart Defects, Congenital / embryology,  ultrasonography*
Hypoplastic Left Heart Syndrome / ultrasonography
Pregnancy Trimester, First
Pregnancy, High-Risk
Prospective Studies
Retrospective Studies
Sensitivity and Specificity
Ultrasonography, Prenatal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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