Document Detail

Early experience and the development of stress reactivity and regulation in children.
MedLine Citation:
PMID:  19481109     Owner:  NLM     Status:  MEDLINE    
Children who spend early portions of their lives in institutions or those maltreated in their families of origin are at risk for developing emotional and behavioral problems reflecting disorders of emotion and attention regulation. Animal models may help explicate the mechanisms producing these effects. Despite the value of the animal models, many questions remain in using the animal data to guide studies of human development. In 1999, the National Institute of Mental Health in the United States funded a research network to address unresolved issues and enhance translation of basic animal early experience research to application in child research. Professor Seymour Levine was both the inspiration for and an active member of this research network until his death in October of 2007. This review pays tribute to his legacy by outlining the conceptual model which is now guiding our research studies.
Michelle M Loman; Megan R Gunnar;
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2009-05-27
Journal Detail:
Title:  Neuroscience and biobehavioral reviews     Volume:  34     ISSN:  1873-7528     ISO Abbreviation:  Neurosci Biobehav Rev     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-02     Completed Date:  2010-08-04     Revised Date:  2014-09-21    
Medline Journal Info:
Nlm Unique ID:  7806090     Medline TA:  Neurosci Biobehav Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  867-76     Citation Subset:  IM    
Copyright Information:
(c) 2009 Elsevier Ltd. All rights reserved.
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MeSH Terms
Child Development / physiology
Models, Biological
Stress, Psychological / genetics,  physiopathology*
Grant Support
R01 MH052135/MH/NIMH NIH HHS; R03 MH060766/MH/NIMH NIH HHS; R03 MH060766-01/MH/NIMH NIH HHS; R03 MH060766-02/MH/NIMH NIH HHS; R21 MH065046/MH/NIMH NIH HHS; R21 MH065046-01/MH/NIMH NIH HHS; R21 MH065046-02/MH/NIMH NIH HHS; R21 MH065046-03/MH/NIMH NIH HHS; R21 MH065046-04/MH/NIMH NIH HHS; R21 MH065046-05/MH/NIMH NIH HHS; R21 MH65046/MH/NIMH NIH HHS
Jacqueline Bruce / ; Mary Dallman / ; Mary Dozier / ; Philip Fisher / ; Nathan Fox / ; Megan Gunnar / ; Kai McCormack / ; Katherine Pears / ; Paul Plotsky / ; Seth Pollak / ; James Ritchie / ; Mar Sanchez / ; Stephen Suomi /

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