Document Detail

Early electrodiagnostic abnormalities in acute inflammatory demyelinating polyneuropathy: A retrospective study of 58 patients.
MedLine Citation:
PMID:  24529487     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Although patients with acute inflammatory demyelinating polyneuropathy (AIDP) are frequently admitted a few days after symptoms onset, electrodiagnostic (EDX) abnormalities in early AIDP are not well characterized. Our aim was to determine the EDX pattern of early AIDP, and, if needed, to propose new EDX diagnostic criteria.
METHODS: In this monocentric study, we retrospectively reviewed the clinical and EDX data of 58 consecutive AIDP patients in whom EDX studies had been performed within 7days after disease onset, representing 46% of all GBS patients admitted in our hospital in an 11years interval.
RESULTS: EDX abnormalities were observed in all patients. The most altered parameters were H reflexes (97% of cases), motor nerve conduction velocities (78%) and distal motor latencies (78%). Only 66% of patients fulfilled the most sensitive published AIDP EDX diagnosis criteria. When using a new set of EDX criteria, which require only one marked EDX abnormality, we observed that 81% of patients could be diagnosed with AIDP.
CONCLUSION: This study suggests that exhaustive EDX studies are always abnormal in early AIDP, and that existing EDX diagnosis criteria can be improved.
SIGNIFICANCE: Our findings are useful for the interpretation of EDX studies in early AIDP.
Jean-Baptiste Chanson; Andoni Echaniz-Laguna
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-1-27
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  -     ISSN:  1872-8952     ISO Abbreviation:  Clin Neurophysiol     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-2-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
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