Document Detail

Early echocardiographic and pulmonary function findings in idiopathic scoliosis.
MedLine Citation:
PMID:  6630493     Owner:  NLM     Status:  MEDLINE    
Thirty-six children and adolescents with early stages of idiopathic scoliosis underwent evaluation by echocardiography and pulmonary function testing. Mildly increased pulmonary vascular resistance was inferred from an elevated ratio of right preejection period to right ventricular ejection time, an increased right ventricular dimension, and a decreased left ventricular dimension. Since neither decreased arterial oxygen saturation nor increased end-tidal expired carbon dioxide partial pressure was seen, desaturation and hypoventilation should not account for these abnormalities. Pulmonary function parameters showed no distinct patterns of abnormality. Even though the patients were divided into two groups by severity of spinal curvature, the cardiopulmonary measures did not correlate with thoracic deformity. Billowing of the mitral leaflets, termed mitral valve prolapse, was demonstrated in 25% of the subjects. Our findings suggest that cardiopulmonary and thoracic changes in idiopathic scoliosis may develop in parallel and may be expressions of a common collagen defect. However, study of sleep and exercise arterial saturation may be required to rule out intermittent hypoxemia as a precipitating factor of cor pulmonale in scoliosis.
F P Primiano; E Nussbaum; S S Hirschfeld; C L Nash; J G Horowitz; M D Lough; C F Doershuk
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of pediatric orthopedics     Volume:  3     ISSN:  0271-6798     ISO Abbreviation:  J Pediatr Orthop     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8109053     Medline TA:  J Pediatr Orthop     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  475-81     Citation Subset:  IM    
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MeSH Terms
Heart Defects, Congenital / complications
Hypertension, Pulmonary / complications
Lung / physiopathology*
Mitral Valve Prolapse / complications
Pulmonary Heart Disease / complications
Respiratory Function Tests
Scoliosis / complications,  physiopathology*,  surgery
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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