Document Detail


Early diagnosis of severe congenital malformations by ultrasonography.
MedLine Citation:
PMID:  7175666     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The significance of ultrasound examinations in early stages of pregnancy is illustrated by the detection of four severe congenital malformations within the first trimester and one malformation syndrome within the first part of the second trimester of pregnancy. We report on the diagnosis of a fetal POTTER syndrome (13 weeks), an anencephalic fetus (13 weeks), MECKEL-GRUBER syndrome (16 weeks), fetal exomphalos (12 weeks) and finally "Siamese twins" (11 weeks). Characteristic ultrasonographic findings are presented and described in detail. The incidence of these severe fetal abnormalities vary between 1:1000 (anencephaly), 1:6000 (exomphalos), 3:10,000 (POTTER-Syndrome), 1:50,000 (MECKEL-GRUBER Syndrome) and 1:250,000 (conjoined twins) live births. The sonographical diagnosis of all these malformation syndromes could be established by thorough and repeated inspection of the fetal head and fetal body with longitudinal and transversal scans. It is concluded, that the high and still increasing reliability congenital structural anomalies renders routine systemic ultrasound screening an attractive possibility already at this "early" stage of pregnancy.
Authors:
W Schmidt; F Kubli
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  10     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  1982  
Date Detail:
Created Date:  1983-02-14     Completed Date:  1983-02-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  233-41     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / diagnosis
Adult
Anencephaly / diagnosis
Congenital Abnormalities / diagnosis*
Female
Hernia, Umbilical / diagnosis
Humans
Kidney / abnormalities
Maternal Age
Pregnancy
Pregnancy, High-Risk
Prenatal Diagnosis / methods*
Twins, Conjoined / diagnosis
Ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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