Document Detail

Early diagnosis of fat embolism syndrome by automated image analysis of alveolar macrophages.
MedLine Citation:
PMID:  8027755     Owner:  NLM     Status:  MEDLINE    
To evaluate the value of automated semiquantitative analysis of fat within alveolar macrophages as an early diagnostic tool for fat embolism syndrome (FES), we investigated 3 patients with respiratory failure following long-bone fractures. The mean area of fat droplets per alveolar macrophage was determined in pixels and, additionally, the percentage of the evaluated areas was calculated. In 2 patients, the diagnosis of FES could be established as early as 24 hr after trauma. Both patients showed an increase in the area of fat per alveolar macrophage (pixels: 851, 1069) as well as in the percentage of fat area per alveolar macrophage area (40.04%, 52.73%), whereas the analysis of the bronchoalveolar lavage (BAL) specimens of a third patient, who later recovered without appearance of clinical signs of FES, revealed only minimal fat content (pixels: 82; 3.82%). Automated semiquantitative analysis of fat within alveolar macrophages may be helpful in the early diagnosis of FES.
A Benzer; D Ofner; M Tötsch; G Klima
Related Documents :
17995675 - Caffeine content of prepackaged national-brand and private-label carbonated beverages.
2891535 - Pharmacokinetics and pharmacodynamics of thiazinamium in asthmatic patients.
24263455 - Interaction of selenium deficiency and fat intake in the regulation of enzymes associat...
8027755 - Early diagnosis of fat embolism syndrome by automated image analysis of alveolar macrop...
19671905 - Adherence to a mediterranean diet, cognitive decline, and risk of dementia.
24782135 - Genetic variations in the leptin gene associated with growth and carcass traits in nell...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical monitoring     Volume:  10     ISSN:  0748-1977     ISO Abbreviation:  J Clin Monit     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-08-09     Completed Date:  1994-08-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8506707     Medline TA:  J Clin Monit     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  213-5     Citation Subset:  IM    
Department of Anesthesiology, University Hospital of Innsbruck, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Embolism, Fat / diagnosis*,  etiology
Fractures, Bone / complications
Image Processing, Computer-Assisted*
Lipids / analysis
Macrophages, Alveolar / chemistry,  pathology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Absence of right superior vena cava that was not detected by insertion of a pulmonary arterial cathe...
Next Document:  Prolonged expression of AP-1 transcription factors in the rat hippocampus after systemic kainate tre...