| Early diagnosis of central nervous system aspergillosis using polymerase chain reaction, latex agglutination test, and enzyme-linked immunosorbent assay. | |
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MedLine Citation:
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PMID: 10460619 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To investigate the usefulness of examination of cerebrospinal fluids (CSF) in the diagnosis of central nervous system (CNS) aspergillosis, we examined five patients with either brain abscesses or cerebral infarctions and 11 control patients. CSF samples were subjected to enzyme-linked immunosorbent assay (EIA), latex agglutination test (LA) and polymerase chain reaction (PCR). Cultures of CSF samples were negative in all the patients, but PCR, EIA and LA were positive in five, four and four patients with CNS aspergillosis, respectively. None of these tests were positive in the control patients. CSF examination may be beneficial in the diagnosis of CNS aspergillosis. |
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Authors:
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M Kami; S Ogawa; Y Kanda; Y Tanaka; U Machida; T Matsumura; H Sakamaki; H Hirai |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British journal of haematology Volume: 106 ISSN: 0007-1048 ISO Abbreviation: Br. J. Haematol. Publication Date: 1999 Aug |
Date Detail:
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Created Date: 1999-10-14 Completed Date: 1999-10-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372544 Medline TA: Br J Haematol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 536-7 Citation Subset: IM |
Affiliation:
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Department of Haematology and Oncology, Faculty of Medicine, University of Tokyo, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aspergillosis / cerebrospinal fluid, diagnosis* Central Nervous System Diseases / diagnosis* Enzyme-Linked Immunosorbent Assay / methods Female Humans Latex Fixation Tests / methods Male Middle Aged Polymerase Chain Reaction / methods |
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