Document Detail


Early detection and successful treatment of cerebral venous thrombosis associated with minimal change nephrotic syndrome.
MedLine Citation:
PMID:  17915622     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although venous thrombosis is a major complication in nephrotic syndrome, cerebral venous thrombosis (CVT) is rarely reported. We describe a 29-year-old male with nephrotic syndrome who suddenly developed headache and nausea. Although computed tomography scan and magnetic resonance imaging detected no abnormal lesions, phase-contrast magnetic resonance venography (PC MRV) demonstrated extensive thrombosis of the superior sagittal sinus. After receiving systemic anticoagulant therapy and oral prednisolone, his neurological symptoms improved dramatically, and complete remission from nephrotic syndrome was achieved. Follow-up PC MRV demonstrated recanalization of the superior sagittal sinus, and renal biopsy confirmed the diagnosis of minimal change nephrotic syndrome. Although CVT is difficult to detect with conventional diagnostic methods, PC MRV may help the establishment of an early diagnosis and prompt treatment for a successful outcome.
Authors:
H Komaba; H Kadoguchi; N Igaki; T Goto
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  68     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-10-05     Completed Date:  2007-12-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  179-81     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Takasago Municipal Hospital, Takasago, Japan. hkomaba@med.kobe-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Early Diagnosis
Humans
Magnetic Resonance Imaging
Male
Nephrosis, Lipoid / complications*,  diagnosis,  therapy
Phlebography
Sagittal Sinus Thrombosis / diagnosis*,  etiology*,  therapy

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